Published 30 September 2011

Some data

1900
Creation on the 15th March of the "Antirabies and Bacteriological Institute of Brabant" (Institut antirabique et bactériologique du Brabant - Antirabiës- en Bacteriologisch Instituut van Brabant).
 
 
1900
Development of the complement fixation reaction test by J. Bordet. 
1900
Production of rabies vaccine and anti-diphtheria serum.
1901
The new institution temporarily moves in March 1901 into the premises of the "Institut de Physiologie Solvay".
1903
New name : Pasteur Institute of Brabant (Institut Pasteur du Brabant – Instituut Pasteur van Brabant).
1906
Discovery of the causal agent of whooping cough by J. Bordet and O. Gengou.
1914
Production of anti-typhoid and gonovaccine.
1919
Preparation, in collaboration with Ruelens, of the Bordet-Ruelens antigen.
1919
Development of the Bordet-Wassermann reaction for the serological diagnosis of syphilis.
1919
Jules Bordet was awarded the Nobel Prize in physiology and medicine for his discoveries relating to immunity
1919
First edition of the "Treatise of immunity in infectious diseases" (Traité de l’Immunité dans les maladies infectieuses"), by Jules Bordet.
1926
Production of pertussis vaccine and diphtheria anatoxin.
1927
Discovery by A. Gratia of a substance with antibiotic activity.
1930
Start of the production of the BCG vaccine against tuberculosis.
1934
Production of tuberculines.
1935
Production of anti-tetanus serum.
1936
Production of tetanus anatoxin.
1942
Production of anti-gangrene serum.
1948
Production of staphylococcal- and cholera vaccine
1951
Establishment of the national center for phage typing and enterobacteria.
1952
Establishment of the "Virology" department.
1955
Development of epidemiological and diagnostic methods for combating the spread of poliomyelitis
1969
Important intervention in the fight against the global cholera epidemic through the production of vaccine.
1975
Development of an efficient immunofluorescnce test for the diagnosis of toxoplasmosis.
1979-1983
Setting up of a laboratory for the detection of mutagens and carcinogens.
1980
First molecular cloning of the human beta interferon gene (with Dr. W. Fiers and Dr. E. De Clercq).
1982
First molecular cloning of the human interleukin-6 gene, a substance that plays a fundamental role in the immune system (with Dr. W. Fiers and Dr. E. De Clercq).
1982
Transfer of the laboratories to Uccle from 1982 to1989.
1983
The Pasteur Institute of Brabant becomes the national reference centre for mycobacteria (tuberculosis), phage typing, hepatitis and botulism (food intoxications).
1983
Establishment of the AIDS unit.
1985
The Pasteur Institute becomes one of the 8 national AIDS reference laboratories.
1987
Cessation of serum- and vaccine production following a decision of the Province of Brabant.
1989
Cloning and sequencing of an important gene for the diagnosis of tuberculosis and the vaccination.
1989
Vaccination campaign in foxes with a recombinant rabiesvaccine.
1995
The Pasteur Institute is transferred to the Ministery of Social Affairs, Public Health and Environment.
1995
The Pasteur Institute becomes a national reference centre of aminoglycoside resistance.
1995-1996
Major achievements on DNA vaccination against tuberculosis and toxoplasmosis.
1999
Eradication of rabies in Belgium by oral vaccination of the fox using a recombinant vaccine.